Section: New Results

Chimeric Transcripts may be Translated

There is now increasing evidence for the existence of so-called Chimeric Transcripts. In contrast to regular transcripts, which are composed of exons located close to each other on the genome, these chimeric transcripts can be composed of exons which are located megabases away, or even on different chromosomes. We showed that these chimeras are lowly expressed, are tissue specific, and that some of them may be translated, yielding proteins with altered function or localisation [13] .